Poly(Trimethylene Carbonate-co-ε-Caprolactone) Promotes Axonal Growth
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منابع مشابه
Poly(Trimethylene Carbonate-co-ε-Caprolactone) Promotes Axonal Growth
Mammalian central nervous system (CNS) neurons do not regenerate after injury due to the inhibitory environment formed by the glial scar, largely constituted by myelin debris. The use of biomaterials to bridge the lesion area and the creation of an environment favoring axonal regeneration is an appealing approach, currently under investigation. This work aimed at assessing the suitability of th...
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Poly (ε-caprolactone), (PCL) or simply polycaprolactone as it is usually referred to, is a synthetic biodegradable aliphatic polyester which has attracted considerable attention in recent years, notably in the biomedical areas of controlled-release drug delivery systems, absorbable surgical sutures, nerve guides, and three-dimensional (3-D) scaffolds, for use in tissue engineering. Various poly...
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Asymmetric telechelic α-hydroxyl-ω-(carboxylic acid)-poly(ε-caprolactone) (HA-PCL), α-hydroxyl-ω-(benzylic ester)-poly(ε-caprolactone) (HBz-PCL) and an asymmetric telechelic copolymer α-hydroxyl-ω-(carboxylic acid)-poly(ε-caprolactone-co-γbutyrolactone) (HA-PCB) were synthesized by ring-opening polymerization of εcaprolactone (CL). CL and CL/γ-butyrolactone mixture were used to obtain homopolym...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0088593